For dogs that hunt in Texas

Chagas Disease is a Serious Threat to Hunting Dogs

Pan American Vet Lab provides accurate ELISA testing for Chagas disease and is developing experimental immunotherapy focused on the immune response that drives clinical disease.

>95%

ELISA sensitivity & specificity

1,021

dogs tested at PAVL

663

positive results, 2022–2025

The hidden risk

Most infected dogs show no signs—until damage is done.

Chagas disease can silently damage the heart. Dogs may appear healthy during early infection and may only be recognized after performance decline, cardiac symptoms, or sudden illness.

Risk is highest for dogs that hunt, live outdoors, train in rural environments, or spend nights in areas where kissing bugs and wildlife reservoirs are present.

If your dog hunts in Texas, testing matters.
  • Bird dogs and retrievers
  • Coonhounds, foxhounds, and cat hounds
  • Hog hunting dogs
  • Outdoor kennel and working dogs

PAVL field data

663 of 1,021 dogs tested positive.

Approximately 65% of dogs tested at Pan American Vet Lab were positive for Chagas exposure.

Data derived from dogs tested at PAVL, 2022–2025.

65%
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  • 663 positive
  • 358 negative

Total tested: 1,021 dogs

ELISA diagnosis

Accurate testing you can act on.

PAVL’s Chagas ELISA is designed to help owners, trainers, and veterinarians know a dog’s status before clinical signs become obvious.

>95%

Sensitivity

>95%

Specificity

1,000+

Dogs tested

Disease biology

Chagas disease is driven by the immune response.

Chagas disease is well documented to be mediated by the host immune response, not just the parasite itself. Infected dogs can have very different outcomes depending on how their immune system responds.

~75%

Non-allergic immune response

Most infected dogs do not develop clinical disease and remain clinically normal.

~25%

Allergic / dysregulated response

Clinically affected dogs display allergic immunity to the parasite and may develop cardiac disease.

Experimental immunotherapy

A new approach: converting the immune response.

PAVL’s experimental immunotherapy is based on the principle that converting clinically ill dogs from allergic immunity to non-allergic immunity may resolve clinical disease in the same manner seen in the majority of infected dogs that remain clinically normal.

Clinical disease

Allergic immune response

Target state

Non-allergic response

Important: This immunotherapy is experimental and under development. Clinical outcomes are subject to ongoing evaluation.

For veterinarians

Diagnostic support for clinical decision-making.

PAVL supports veterinarians managing dogs with suspected Chagas exposure, especially hunting and working dogs that travel to or hunt in Texas.

Testing: ELISA diagnostic support with >95% sensitivity and specificity.

Disease model: Immune-mediated clinical progression with allergic versus non-allergic response patterns.

Therapy status: Experimental immunotherapy under development.

Don’t wait for symptoms.

Approximately 65% of dogs tested at Pan American Vet Lab were positive for Chagas exposure.

Selected scientific and public-health references

  • CDC: Chagas disease is caused by Trypanosoma cruzi and is transmitted by triatomine insects.
  • CDC Emerging Infectious Diseases: Texas is a high-risk state for canine T. cruzi exposure.
  • Peer-reviewed literature describes Chagas heart disease as an inflammatory cardiomyopathy with immune-mediated pathology.